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Research Technician II

Requisition Details

Requisition Information

Requisition Title Research Technician II
Requisition Number 01650-R

Opening Information

Job Status Full Time
Position Category Science/Research
Education Required Undergraduate Degree
Experience Required 3 - 5 Years
Position Description

Research Technician II

A research laboratory at Cold Spring Harbor Laboratory, run by Nick Tonks, is seeking a highly motivated and organized candidate for an immediate opening for a Laboratory Technician.

The Tonks lab studies the regulation of signal transduction by protein phosphorylation. In particular, they focus on characterizing the structure, regulation and mechanism of action of the protein tyrosine phosphatase (PTP) family of enzymes. Overall, the goal is to devise creative new approaches to exploiting the PTPs as targets for therapeutic intervention in major human diseases, including diabetes, obesity, neurological disorders and cancer.

The lab technician will work under the supervision of the Principal Investigator and the main responsibility will be to test potential small molecule drug candidates in disease models, including the implementation of various assays to test for effects of the compounds on signaling pathways.

Position Requirements

EDUCATION: Bachelor’s or Master’s degree in a relevant subject area.

EXPERIENCE: 2 plus years of experience in a protein biochemistry or molecular biology lab, or a Master’s degree in a relevant scientific discipline. Excellent organizational skills, strong communication skills, and ability to work independently are important characteristics for a successful candidate.

Previous experience in an experimental laboratory is important. Experience in any of the following techniques would be advantageous:
• Recombinant protein expression/purification, including general chromatographic methods.
• Experience in implementing biochemical assays, including enzymatic activity (fluorophore, radiolabeling and gel electrophoresis-based) and protein binding (small molecule and protein-protein interactions) assays.
• Experience in routine molecular biology and cloning techniques, including plasmid/construct generation and production of various competent cells (such as BL21-DE3 E. coli).
• Experience in mammalian tissue culture, including immunochemical applications (immunoblotting, fluorescence etc.) and protein overexpression (including transient and stable cell line preparation)

We offer a competitive salary and a comprehensive benefits package.


Interested candidates can apply for the position at:

Position number: 01650-R

Cold Spring Harbor Laboratory is a non-profit research institution located on the North Shore of Long Island that has been at the forefront of biology research for over 125 years. Home to eight Nobel Laureates over the years, Cold Spring Harbor Laboratory provides an immersive and highly-collaborative research environment about 45 minutes outside of New York City. Cold Spring Harbor Laboratory is an NCI-designated Cancer Center, and every year over 10,000 scientists journey to the Labs to attend one of CSHL’s famous Meetings and Courses.

For more information about CSHL, please Visit us at

CSHL is an EO/AA Employer. All qualified applicants will receive consideration for employment and will not be discriminated against on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability or protected veteran status.

VEVRAA Federal Contractor

Requisition Specific Questions

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Applicant Documents

Required Documents
  1. Resume or Curriculum Vitae
  2. Cover Letter
Optional Documents